Researchers Develop Vaccine to Treat Multiple Allergies with a Single Treatment
An international team of researchers led by the Technical University of Denmark (DTU), in collaboration with the Complutense University of Madrid (UCM), IBIMA-Plataforma BIONAND (Málaga), and medical specialists from the Vall d’Hebron and Clínic hospitals in Barcelona, has developed an RNA-based vaccine that opens the door to treating multiple allergies with a single treatment, as it has managed to neutralize the effects of both food and pollen allergens in an animal model.
TL;DR
- An international team has developed an RNA-based vaccine to treat multiple food and pollen allergies with a single treatment.
- The vaccine uses an artificial consensus allergen delivered via messenger RNA, prompting the body's cells to produce the allergen and induce an immune response.
- This approach aims to overcome the limitations of current allergy treatments, which are often long, may not guarantee complete protection, and can cause adverse reactions.
- Animal model studies demonstrated the vaccine's ability to neutralize allergens from diverse sources and provide protection exceeding that of individual natural allergens.
- The treatment was found to be safe in the studied models, with no adverse reactions during immunization.
- This breakthrough could offer a new therapeutic avenue for the millions affected by complex allergies, including the nsLTP syndrome prevalent in Southern Europe.