health

New method advances cancer detection with blood test

The possibility of diagnosing diseases such as cancer earlier and more accurately through a simple and inexpensive blood test is closer than ever. A study published in the journal Proceedings of the National Academy of Sciences (Pnas) presents a new method called MethylScan, developed by researchers at the University of California [...]

New method advances cancer detection with blood test

TL;DR

  • MethylScan, developed by UCLA researchers, is a new blood test for early disease detection.
  • It analyzes DNA methylation in circulating free DNA (cfDNA), which reflects tissue health.
  • The test overcomes the challenge of background noise by selectively removing DNA from normal blood cells.
  • Initial tests showed 98% specificity and detected about 63% of cancers overall, and 55% in early stages.
  • It can also identify the tissue of origin for abnormal signals.
  • The estimated cost of the test once commercialized is around $20.